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June 9, 2011

Colin Firth: Actor. Writer. Academy Award Winner. Scientist?

Colin Firth

Colin Firth, a king AND a scientist. © The Weinstein Company/courtesy Everett Collection

Ideas for scientific experiments come from all sorts of places (and fewer of them originate in the lab than you might think). A study on political orientation and brain structure, published in Current Biology, for example, got its start when the actor Colin Firth—credited as a co-author on the paper—was guest-editing a BBC Radio 4 program called “Today.” “This struck me as an opportunity to explore things which compel me…but about which I’m perhaps not sufficiently informed,” he told host Justin Webb. “I…decided to find out what was biologically wrong with people who don’t agree with me and see what scientists had to say about it.” Or to put it a bit more nicely, to see if the brains of people with different political leanings were truly different.

Ryota Kanai and Geraint Rees of University College London took that idea and ran with it. They performed MRI scans of 90 college students who had been asked about their political attitudes, and then looked at various structures in the brain. They found that a greater amount of gray matter in the anterior cingulate cortex was associated with liberalism and a greater amount in the amygdala was associated with conservatism. They confirmed the finding in a second set of 28 participants.

These findings are consistent with previous studies showing greater brain activity in the anterior cingulate cortex of liberals. One of the jobs of that area of the brain is to monitor uncertainty and conflicts. “Thus, it is conceivable that individuals with a larger ACC have a higher capacity to tolerate uncertainty and conflicts, allowing them to accept more liberal views,” the scientists write.

The amygdala, on the other hand, processes fear, and previous studies have shown that conservatives respond more aggressively in threatening situations. “Our findings are consistent with the proposal that political orientation is associated with psychological processes for managing fear and uncertainty,” the researchers write.

Still unknown, however, is which comes first, the brain structure or the beliefs. The researchers would have to expand their study to see if there are changes in brain structure before or after a person changes their political leanings.

Perhaps Firth could sign up as a volunteer.



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2 Comments »

  1. Jay_C says:

    Amygdala volume correlates positively with both the size (the number of contacts a person has) and the complexity (the number of different groups to which a person belongs) of social networks.[39][40] Individuals with larger amygdalae had larger and more complex social networks. They were also better able to make accurate social judgments about other persons’ faces.[41] It is hypothesized that larger amygdalae allow for greater emotional intelligence, enabling greater societal integration and cooperation with others.[42]

    The amygdala processes reactions to violations concerning personal space. These reactions are absent in persons in whom the amygdala is damaged bilaterally.[43] Furthermore, the amygdala is found to be activated in fMRI when people observe that others are physically close to them, such as when a person being scanned knows that an experimenter is standing immediately next to the scanner, versus standing at a distance.[43]

    39.^ Bickart, Kevin C., Wright, Christopher I., Dautoff, Rebecca J., Dickerson, Bradford C., Barrett, Lisa Feldman (Dec. 2010). “Amygdala volume and social network size in humans”. Nature neuroscience 14 (2): 163–164. doi:10.1038/nn.2724. PMC 3079404. PMID 21186358. http://www.nature.com/neuro/journal/vaop/ncurrent/full/nn.2724.html. Retrieved 2010-12- 27.
    40.^ Szalavitz, Maia (December 28, 2010). “How to Win Friends: Have a Big Amygdala?”. Time Healthland. Time.com. http://healthland.time.com/2010/12/28/how-to-win-friends-have-a-big-amygdala/?xid=rss-topstories. Retrieved December 30, 2010.
    41.^ Bzdok, D., Langner, R., Caspers, S., Kurth, F., Habel, U., Zilles, K., Laird, A., Eickhoff, S.B., 2011. ALE meta-analysis on facial judgments of trustworthiness and attractiveness. Brain Struct Funct 215, 209-223.
    42.^ Buchanan, T.W., Tranel, D. & Adolphs, R. in The Human Amygdala (eds. Whalen, P.J. & Phelps, E.A.) 289–318 (Guilford, New York, 2009).
    43.^ a b Kennedy DP, Gläscher J, Tyszka JM, Adolphs R (2009). “Personal space regulation by the human amygdala”. Nat Neurosci 12 (10): 1226–1227. doi:10.1038/nn.2381. PMC 2753689. PMID 19718035.

  2. For a person who never finished highschool or attended a university, Colin Firth shoows a quality of curiosity, intelligence and the ability to pursue an interesting question, I cannot tell you how many times I have listened to politicians and have said aloud “What the devil is in their brains?”

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